Abstract: The wind data observed by the gradient wind observation system set on 100 m high tower in Donghai Island meteorology station located in Zhanjiang, Guangdong Province are compared with the wind data measured by WINDCUBE V2 pulse laser wind profiler installed at the same site from 21 May to 16 August in 2012. Based on time synchronization adjustment, validity test and sample selection, a comparative analysis is conducted using several wind parameters observed at heights of 50 m, 65 m, 70 m, 100 m by cup anemometer, ultrasonic anemometer and WINDCUBE V2 under weak wind, strong wind, sunny and rainy days.Results show that fitting degrees of horizontal wind parameters are quite good. Fitting degrees of wind speed and wind direction measured by WINDCUBE V2 and cup anemometer are up to more than 0.99. The fitting degree of 3 s gust wind speed is over 0.96. Fitting degrees of 3 s gust wind speed, turbulence intensity and wind speed standard deviation are over 0.96, 0.67 and 0.79, respectively. The WINDCUBE V2 performs a little better under strong wind and no rainfall condition when measuring the above wind parameters. Fitting degrees of wind speed and wind direction of strong wind samples are a litter larger than that of weak wind samples. More than 90% strong wind speed relative deviation vary between-4.5% and 2.5% while more than 90% wind speed relative deviation vary between-11.5% and 5.5% under weak wind condition. Overall, the precipitation has no obvious influence on the measurement of wind speed, wind direction, turbulence intensity and gust wind speed by WINDCUBE V2 when the 10 min rainfall intensity is less than 15 mm while measurements of wind speed standard deviation are a bit influenced by precipitation. Fitting degrees of wind speed and wind direction of samples without rain are a litter larger than that on rainy days, but both are over 0.99. The WINDCUBE V2 performs weaker at the vertical airflow velocity measurement under the increasing of horizontal wind speed and the precipitation. The fitting degree of vertical airflow velocity is 0.872 when the horizontal wind speed is between 0-1.5 m·s^-1. But the fitting degree of vertical airflow velocity decreases to 0.25 when the horizontal wind speed increases to 0-6 m·s^-1. The vertical airflow velocity measured by WINDCUBE V2 decreases more significantly with the stronger rainfall. When 1 min rainfall intensity is over 0.5 mm, the vertical airflow velocity measured by WINDCUBE V2 is found to be 4 m·s^-1 less than the measurement of ultrasonic anemometer. These results can provide some technical references for the reliability test method of laser wind profiler measured data.