Abstract: According to computer resources disposition in Shanghai Meteorological Bureau and numerical forecast products of National Meteorological Center, a new operational numerical prediction system of Shanghai regional Meteorological Center is set up with the model frame of NCAR-PSU/MM4, and the former operational system of five level nested model is renewed. According to whether there is tropical cycle or not getting to the domain, the typhoon model or limited-area model is carried out, respectively. Through one year operation, it is shown that the computation of new operational system is of stability and there is a good prediction effect. In the meantime the forecast products, including the surface element predictions every 6 h for 25 cities in East China, can be provided for provincial meteorological Burean in the regional center.