Abstract: Based on the fourty years meteorological data in the region of Yarlung Zangbo Jiang river, Lhasa He river and Nianchu He river of Tibet, climate change of this region is analysed. It is shown that there is the trend of temperature raising and precipitation decreasing. The impacts of future climate change on agriculture, livestock husbandry, water resources and ecological environment are analysed. It is suggested that possible policy and measures should be taken for adapting to the climate change