Based on reflectance method, vicarious radiometric calibration of remote sensing data from Airborne Moderate Resolution Imaging Spectrometer (AMODIS) is described. The results show that the calibration coefficients at two flying altitudes from 17 channels of visible and near infrared region were, respectively, in coincidence, and the relative difference was between 0.19% and 3.89%. Also the retrieval values from AMODIS in the model flying experiment were coincided with the observations of surface synoptic station